40 search results for “Oncology”
We foster an environment in which early-career scientists can work together in dedicated projects on tough preclinical challenges to help lay the groundwork for a new generation of therapies
Learn more about the facts and figures of our BioMed X Institute.
The objective of the group will be to investigate the formation, maintenance and consequences of extrachromosomal DNA (ecDNA) in cancer using cutting edge single-cell screening and spatial technologies.
Completed Projects · Oncology Team DDC DNA Damage in Cancer Often termed as a disease of the genome, cancer is the result of random acquisition of mutations that activate oncogenes and inactivate tumor suppressors. Consequently, cellular processes including cell cycle control, transcription, apoptosis and DNA repair are affected, conferring incremental growth advantages to cells and fomenting tumo …
The group aims to translate new synthetic lethal interactions between DNA repair genes into novel therapeutic targets in oncology.
Our management and project teams are regularly represented at events and report there about BioMed X and our ongoing research.
For us at BioMed X, publishing the results of our research projects in peer-reviewed journals is key. We also share results at national and international meetings and workshops. We think this is vital to building collaborations and stimulating cross-fertilization of ideas and methods.
At the BioMed X Institute, we are working with different state-of-the-art research tools and methods, emerging from the different research projects. As a Special Interest Group, we continuously grow our internal spectrum of laboratory tools and methods.
Fellowships at BioMed X are limited to a defined project term. During this period, all fellows focus their attention on biomedical research as well as personal growth in order to get ready for their next big challenge in academia, industry or a startup. The Special Interest Group “Career Development” is a grassroots initiative of BioMed X fellows organizing events and training courses.
Completed Projects · Oncology Team IMT Immunosuppressive Microenvironment of Tumors Solid tumors are complex microenvironments composed of cancer and immune cells that interact through various regulatory networks. Although CD8 T-cells may recognize and kill tumor cells, their function is impaired by cells such as regulatory T-cells, tumor-associated macrophages (TAM), and myeloid-derived suppresso …