21 search results for “Oncology”
We foster an environment in which early-career scientists can work together in dedicated projects on tough preclinical challenges to help lay the groundwork for a new generation of therapies
Our management and project teams are regularly represented at events and report there about BioMed X and our ongoing research.
For us at BioMed X, publishing the results of our research projects in peer-reviewed journals is key. We also share results at national and international meetings and workshops. We think this is vital to building collaborations and stimulating cross-fertilization of ideas and methods.
At the BioMed X Institute, we are working with different state-of-the-art research tools and methods, emerging from the different research projects. As a Special Interest Group, we continuously grow our internal spectrum of laboratory tools and methods.
Fellowships at BioMed X are limited to a defined project term. During this period, all fellows focus their attention on biomedical research as well as personal growth in order to get ready for their next big challenge in academia, industry or a startup. The Special Interest Group “Career Development” is a grassroots initiative of BioMed X fellows organizing events and training courses.
Completed Projects · Oncology Team IMT Immunosuppressive Microenvironment of Tumors Solid tumors are complex microenvironments composed of cancer and immune cells that interact through various regulatory networks. Although CD8 T-cells may recognize and kill tumor cells, their function is impaired by cells such as regulatory T-cells, tumor-associated macrophages (TAM), and myeloid-derived suppresso …
Completed Projects · Oncology Team SKI Selective Kinase Inhibitors Protein kinases have been a major target of drug discovery programs for many years due to their central roles in signaling pathways involved in the formation and progression of human cancer, inflammation and Alzheimer’s disease. Most kinase inhibitors that are currently approved and in development bind to the highly conserved ATP-b …
Completed Projects · Oncology Team MSC Metabolism and Signaling in Cancer Owing to stressful microenvironments and the accumulation of mutations favoring adaption, cancer cells frequently show alterations in metabolic and other signaling circuits compared with normal cells. As a consequence, cancer cells show increased dependence on certain proteins or stress-support pathways, which themselves mig …
The team is seeking new platform technologies or concepts which lead to identification of antigens recognized by T cells involved in autoimmune responses.
Accelerate the pace of innovation in preclinical research. Become a partner and join the BioMed X Institute.
We are a team of highly diverse people from many different countries working on the same ambitious goals.
BioMed X is an independent research institute operating at the interface between academia and industry.
Splicing of mRNA is a crucial process in eukaryotic gene expression regulation, and aberrant splicing plays a critical role in the pathogenesis of several molecular subtypes of cancer. Such splicing abnormalities can lead to constitutive activity of oncogenes, reduced expression of tumor suppressors, or drug resistance. Our team is seeking to identify key molecular mechanisms that generate mRNA sp …
Contact us If you have questions about the BioMed X Institute, please do not hesitate to contact us. BioMed X GmbH Im Neuenheimer Feld 515 69120 Heidelberg, Germany +49 6221 426 11 0 +49 6221 426 11 22 firstname.lastname@example.org Im Neuenheimer Feld 515 Management & Support Team Team PMI Group Leader: Bachir El Debs Team IEB Group Leader: Martin Resnik Docampo Team EPD Group Leader: Ebru Ercan Herbst Im Neuenheim …
Often termed as a disease of the genome, cancer is the result of random acquisition of mutations that activate oncogenes and inactivate tumor suppressors. Consequently, cellular processes including cell cycle control, transcription, apoptosis and DNA repair are affected, conferring incremental growth advantages to cells and fomenting tumorigenesis.
We identify and attract the best early-career researchers at the best universities and research institutions who are interested to work on our challenges to make a real impact in research for the benefit of patients.