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Oncology

Team SDR

Synthetic Lethality in DNA Repair

The group aims to translate new synthetic lethal interactions between DNA repair genes into novel therapeutic targets in oncology. By performing targeted pooled screens in cells deficient in DNA repair genes, team SDR will strive to identify and characterize new drug targets in DNA repair and DNA replication as a potent tool to increase the efficiency of clinically used DNA damaging agents.

Mentors

Dr. Balca Mardin
Head of Laboratory, DNA Damage Response Research at Merck (Industry mentor)
Dr. Amir Abdollahi
Translational Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg (Academic mentor)

Our Team Members

Dr. Özdemirhan Serçin

Group Leader

Short Bio

2016 – 2021: Postdoctoral Researcher, Team DDC, BioMed X Institute, Heidelberg, Germany
2012 – 2015: Postdoctoral research fellow in the laboratory of Prof. Dr. Cedric Blanpain, IRIBHM, Université Libre de Bruxelles, Belgium
2006 – 2011: PhD Student and research assistant in the laboratory of Prof. Dr. Aziz Sancar, Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, NC, USA

Contact

Dr. Raktim Biswas

Postdoctoral Researcher

Short Bio

2018 – 2022: Postdoctoral Researcher, Department of Biology, Faculty of Medicine, Masaryk University, Brno, Czech Republic
2015 – 2016: Postdoctoral Scholar, Department of Biology, University of Louisville, Kentucky, USA
2012 – 2018: Postdoctoral Researcher, Beckman Laser Institute Korea, Cheonan, South Korea
2007 – 2011: PhD in Molecular Biology, University of Kalyani, Kalyani, India

Contact

Manisha Manojkumar Singh

Research Assistant

Short Bio

2017 – 2020: Master of Science in Molecular Biosciences, Major Cancer Biology, Heidelberg University and DKFZ, Germany
2019: Internship at Broad Institute of MIT and Harvard, Boston, USA
2012 – 2016: Bachelor of Engineering, BMSCE, Bangalore, India

Contact

Amelia Kurti

Master's Student

Short Bio

2022 – present: Master of Science in Molecular Biosciences, Major in Cancer Biology, Heidelberg University and DKFZ, Germany
2022: Internship and Thesis preparation at Thomas Graf laboratory, CRG, Spain
2019 – 2022: Bachelor of Science in Genomics, University of Bologna, Italy

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Berçin Yildiran

Master's Student

Short Bio

2022 – present: Master of Science in Molecular Biosciences, Molecular and Cellular Biology Major, Heidelberg University, Germany
2021: Internship at the University of Copenhagen, Protein Biology Laboratory, Denmark
2017 – 2022: Bachelor of Science in Genetics and Bioengineering, Yeditepe University, Istanbul, Turkey

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Seyedehsaba Nateghi

Intern

Short Bio

2022 – present: Erasmus+ International Master’s in Innovative Medicine (IMIM), Medical Faculty Mannheim, Heidelberg University, Germany
2020 – 2021: Student intern at the Elite Foundation of Iran, Laboratory of Advanced Medical Biotechnology, Iran
2017 – 2021: Bachelor’s in Biology, Department of Microbiology, University of Tehran, Iran

Contact

Preeti Thiyagarajan

Master's Student

Short Bio

2021 – current: Master’s Student in Radiation Biology at the Technical University of Munich, Germany
2021 – 2022: Internships at the Institut für Radiobiologie der Bundeswehr, and at LMU Klinikum, at the Comprehensive Childhood Research Center, Munich, Germany
2017 – 2021: Bachelor’s (Honours) in Advanced Biomedical Sciences at Sri Ramachandra Medical University, India

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Team SDR Alumni

At BioMed X we care for the people who work with us. Staying in touch with those who left but mainly contributed to BioMed X’s success is key. That’s why they have their designated place on our website. So let’s keep connected!

Yuliia Borysovych

Contact

No contact information available.

Izlem Su Akan

Contact

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Team SDR

Our Team Members

Dr. Özdemirhan Serçin

Dr. Raktim Biswas

Manisha Manojkumar Singh

Amelia Kurti

Berçin Yildiran

Seyedehsaba Nateghi

Preeti Thiyagarajan

Team SDR Alumni

Yuliia Borysovych

Izlem Su Akan

Learn more about BioMed X

Team RSC

Team EDC