Team SDR


Team SDR

Synthetic Lethality in DNA Repair

The group aims to translate new synthetic lethal interactions between DNA repair genes into novel therapeutic targets in oncology. By performing targeted pooled screens in cells deficient in DNA repair genes, team SDR will strive to identify and characterize new drug targets in DNA repair and DNA replication as a potent tool to increase the efficiency of clinically used DNA damaging agents.

  • Dr. Balca Mardin
    Head of Laboratory, DNA Damage Response Research at Merck (Industry mentor)
  • Dr. Amir Abdollahi
    Translational Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg (Academic mentor)
The research of this team is kindly sponsored by Merck.

Our Team Members

Dr. Özdemirhan Serçin

Group Leader

 Short Bio
  • 2016 – 2021: Postdoctoral Researcher, Team DDC, BioMed X Institute, Heidelberg, Germany
  • 2012 – 2015: Postdoctoral research fellow in the laboratory of Prof. Dr. Cedric Blanpain, IRIBHM, UniversitĂ© Libre de Bruxelles, Belgium
  • 2006 – 2011: PhD Student and research assistant in the laboratory of Prof. Dr. Aziz Sancar, Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, NC, USA

Dr. Raktim Biswas

Senior Scientist

 Short Bio
  • 2018 – 2022: Postdoctoral Researcher, Department of Biology, Faculty of Medicine, Masaryk University, Brno, Czech Republic
  • 2015 – 2016: Postdoctoral Scholar, Department of Biology, University of Louisville, Kentucky, USA
  • 2012 – 2018: Postdoctoral Researcher, Beckman Laser Institute Korea, Cheonan, South Korea
  • 2007 – 2011: PhD in Molecular Biology, University of Kalyani, Kalyani, India

Manisha Manojkumar Singh

Research Assistant

 Short Bio
  • 2017 – 2020: Master of Science in Molecular Biosciences, Major Cancer Biology, Heidelberg University and DKFZ, Germany
  • 2019: Internship at Broad Institute of MIT and Harvard, Boston, USA
  • 2012 – 2016: Bachelor of Engineering, BMSCE, Bangalore, India

Finn Grözinger

Master's Student

 Short Bio
  • 2021 – ongoing: Master of Science in Molecular Biosciences, Majoring in Molecular and Cellular Biology, Heidelberg University, Germany
  • 2023: Visiting Graduate Student at the Dana-Farber Cancer Institute, Boston, USA
  • 2018 – 2021: Bachelor of Science in Biology, Goethe Universität Frankfurt, Frankfurt am Main, Germany

Team SDR Alumni

At BioMed X we care for the people who work with us. Staying in touch with those who left but mainly contributed to BioMed X’s success is key. That’s why they have their designated place on our website. So let’s keep connected!

Yuliia Borysovych

No contact information available.

Preeti Thiyagarajan


Saheri Sikdar


Amelia Kurti


Berçin Yildiran


Izlem Su Akan


Seyedehsaba Nateghi