Immunology

Team TMI

Translocation of Complex Macromolecules Across the Intestinal Epithelial Barrier

The main objective of the research group TMI is to discover novel transport mechanisms in the human intestinal tract which could be utilized for oral-systemic delivery of diverse therapeutic modalities (e.g., peptides, oligonucleotides, and antibodies). Studies involve screening of ligands, generating intestinal organoids from murine and human subjects, isolating intestinal cells, and creating a co-culture system. The project’s objectives are to develop a ligand specific for a target cell and establish quantitative assessment methods to monitor macromolecular drug delivery across the intestinal epithelial barrier. Our final goal is to create a novel delivery platform, which can be utilized for the development of a new generation of oral immunotherapies for the benefit of patients.

  • Mentors
    • Dr. Steve Baker
      SDir Novel Platforms Immunology Discovery, Janssen Immunosciences, Spring House, USA (Industry mentor)
The research of this team is kindly sponsored by Janssen.

Our Team Members

Dr. Kyungbo Kim

Group Leader

  • Short Bio
    • 2018-2021: Post-doc in Insect development and molecular biology with Prof. Subba Reddy Palli, the University of Kentucky Department of Entomology, USA
    • 2013-2018: PhD in Pharmaceutical sciences in the Laboratory of Prof. Chang-Guo Zhan, the University of Kentucky College of Pharmacy, USA
    • 2012-2013: RA in Cancer biology in the Laboratory of Prof. Wooin Lee, the University of Kentucky College of Pharmacy, USA
    • 2009-2011: MS in Biotechnology in the Laboratory of Prof. ‪Dong-Eun Kim, Konkuk University, Korea
  • Contact

Olivia Müllertz

Research Assistant

  • Short Bio
    • 2020-2021: Master of Science in Pharmaceutical Sciences, University of Copenhagen, Denmark
    • 2020: Research Placement, Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, Australia
    • 2018-2019: Undergraduate Research Assistant, Department of Drug Design and Pharmacology, University of Copenhagen, Denmark
  • Contact

Team TMI Alumni

At BioMed X we care for the people who work with us. Staying in touch with those who left but mainly contributed to BioMed X’s success is key. That’s why they have their designated place on our website. So let’s keep connected!

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