Scientific Publications – Publishing the results of our research projects in peer-reviewed journals is key

Scientific Publications

To learn more about the success of our ongoing and completed projects explore our researcher’s scientific publications.

  • Metabolism and Signaling in Cancer (MSC)
    1. Ignashkova TI, Gendarme M, Peschk K, Eggenweiler HM, Lindemann RK, Reiling JH (2017):
      Cell survival and protein secretion associated with Golgi integrity in response to Golgi stress-inducing agents
      Traffic 18(8)
    2. RamĂ­rez-Peinado S, Ignashkova TI, van Raam BJ, Baumann J, Sennott EL, Gendarme M, Lindemann RK, Starnbach MN, Reiling JH (2017):
      TRAPPC13 modulates autophagy and the response to Golgi stress
      Journal of Cell Science 130
    3. van Raam BJ, Lacina T, Lindemann RK, Reiling JH (2017):
      Secretory stressors induce intracellular death receptor accumulation to control apoptosis
      Cell Death and Disease 8(10)
    4. Gendarme M, Baumann J, Ignashkova TI, Lindemann RK, Reiling JH (2017):
      Image-based drug screen identifies HDAC inhibitors as novel Golgi disruptors synergizing with JQ1
      Molecular Biology of the Cell 28(26)
    5. Baumann J, Ignashkova TI, Chirasani SR, RamĂ­rez-Peinado S, Alborzinia H, Gendarme M, Kuhnigk K, Kramer V, Lindemann RK, Reiling JH (2017):
      Golgi stress-induced transcriptional changes mediated by MAPK signaling and three ETS transcription factors regulate MCL1 splicing
      Molecular Biology of the Cell 29(1)
    6. Alborzinia H, Ignashkova TI, Dejure FR, Gendarme M, Theobald J, Wölfl S, Lindemann RK, Reiling JH (2018):
      Golgi stress mediates redox imbalance and ferroptosis in human cells
      Communications Biology 1

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  • Selective Kinase Inhibitors (SKI)
  • Immunosuppressive Microenvironment of Tumors (IMT)
    1. Schröder M, Loos S, Naumann SK, Bachran C, Krötschel M, Umansky V, Helming L, Swee LK (2017):
      Identification of inhibitors of myeloid-derived suppressor cells activity through phenotypic chemical screening
      OncoImmunology 6(1)
    2. Bachran C, Schröder M, Conrad L, Cragnolini JJ, Tafesse FG, Helming L, Ploegh HL, Swee LK (2017):
      The activity of myeloid cell-specific VHH immunotoxins is target-, epitope-, subset- and organ dependent
      Scientific Reports 7(1)
    3. Schröder M, Krötschel M, Conrad L, Naumann SK, Bachran C, Rolfe A, Umansky V, Helming L, Swee LK (2018):
      Genetic screen in myeloid cells identifies TNF-α autocrine secretion as a factor increasing MDSC suppressive activity via Nos2 up-regulation
      Scientific Reports 8
    4. Wöll S, Schiller S, Bachran C, Swee LK, Scherließ R (2018):
      Pentaglycine lipid derivates – rp-HPLC analytics for bioorthogonal anchor molecules in targeted, multiple-composite liposomal drug delivery systems
      International Journal of Pharmaceutics 547(1-2)
    5. Wöll S, Bachran C, Schiller S, Schröder M, Conrad L, Swee LK, Scherließ R (2018):
      Sortaggable liposomes: Evaluation of reaction conditions for single-domain antibody conjugation by Sortase-A and targeting of CD11b+ myeloid cells
      European Journal of Pharmaceutics and Biopharmaceutics 133
    6. Wöll S, Bachran C, Schiller S, Schröder M, Conrad L, Scherließ R, Swee LK (2019):
      Sortagging of liposomes with a murine CD11b-specific VHH increases in vitro and in vivo targeting specificity of myeloid cells
      European Journal of Pharmaceutics and Biopharmaceutics 134

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  • Epigenetics and COPD (EAC)
    1. Jurkowska RZ, Jurkowski TP (2019):
      Establishment, erasure and synthetic reprogramming of DNA methylation in mammalian cells
      In: The DNA, RNA, and histone methylomes (Springer)
    2. Llamazares Prada M, Espinet E, Mijosek V, Schwartz U, Waszak SM, Lutsik P, Tamas R, Richter M, Behrendt A, Pohl S, Benz N, Muley T, Warth A, Heussel CP, Winter H, Herth F, Mertens T, Karmouty-Quintana H, Koch I, Benes V, Korbel JO, Trumpp A, Wyatt D, Stahl H, Plass C, Jurkowska RZ (2020):
      Versatile workflow for cell type resolved transcriptional and epigenetic profiles from cryopreserved human lung
      bioRxiv

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  • Nanomaterial-Based Biosensors (NBB)
    1. Gutiérrez-Sanz Ó, Andoy NM, Filipiak MS, Haustein N, Tarasov A (2017):
      Direct, label-free, and rapid transistor-based immunodetection in whole serum
      ACS Sensors 2(9)
    2. Filipiak MS, Rother S, Andoy NM, Knudsen AC, Grimm S, Bachran C, Swee LK, Zaumseil J, Tarasov A (2018):
      Highly sensitive, selective and label-free protein detection in physiological solutions using carbon nanotube transistors with nanobody receptors
      Sensors and Actuators B: Chemical 255(2)
    3. Andoy NM, Filipiak MS, Vetter D, Gutiérrez-Sanz Ó, Tarasov A (2018):
      Graphene-based electronic immunosensor with femtomolar detection limit in whole serum
      Advanced Materials Technologies 3(12)
    4. Haustein N, Gutiérrez-Sanz Ó, Tarasov A (2019):
      Analytical model to describe the effect of poly-ethylene glycol on ionic screening of analyte charges in transistor-based immunosensing
      ACS Sensors 4(4)
    5. Gutiérrez-Sanz Ó, Haustein N, Schroeter M, Oelschlaegel T, Filipiak MS, Tarasov A (2019):
      Transistor-based immunosensing in human serum samples without on-site calibration
      Sensors and Actuators B: Chemical 295
    6. Filipiak MS, Vetter D, Thodkar K, Gutiérrez-Sanz Ó, Jönsson-Niedziółka M, Tarasov A (2020):
      Electron transfer from FAD-dependent glucose dehydrogenase to single-sheet graphene electrodes
      Electrochimica Acta 330
    7. García-Chamé MA, Gutiérrez-Sanz Ó, Ercan-Herbst E, Haustein N, Filipiak MS, Ehrnhöfer DE, Tarasov A (2020):
      A transistor-based label-free immunosensor for rapid detection of tau protein
      Biosensors and Bioelectronics

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  • Tau-Mediated Neurodegeneration in Alzheimer’s Disease (TNA)
    1. Ercan E, Eid S, Weber C, Kowalski A, Bichmann M, Behrendt A, Matthes F, Krauss S, Reinhardt P, Fulle S, Ehrnhoefer DE (2017):
      A validated antibody panel for the characterization of tau post-translational modifications
      Molecular Neurodegeneration 12(1)
    2. Schöndorf DC, Elschami M, Schieck M, Ercan-Herbst E, Weber C, Riesinger Y, Kalman S, Steinemann D, Ehrnhoefer DE (2018):
      Generation of an induced pluripotent stem cell cohort suitable to investigate sporadic Alzheimer’s Disease
      Stem Cell Research 34
    3. Behrendt A, Bichmann M, Ercan-Herbst E, Haberkant P, Schöndorf DC, Wolf M, Fahim SA, Murolo E, Ehrnhoefer DE (2019):
      Asparagine endopeptidase cleaves tau at N167 after uptake into microglia
      Neurobiology of Disease 130
    4. Ercan-Herbst E, Ehrig J, Schöndorf DC, Behrendt A, Klaus B, Gomez Ramos B, Prat Oriol N, Weber C, Ehrnhoefer DE (2019):
      A post-translational modification signature defines changes in soluble tau correlating with oligomerization in early stage Alzheimer’s disease brain
      Acta Neuropathologica Communications 7(1)
    5. García-Chamé MA, Gutiérrez-Sanz Ó, Ercan-Herbst E, Haustein N, Filipiak MS, Ehrnhöfer DE, Tarasov A (2020):
      A transistor-based label-free immunosensor for rapid detection of tau protein
      Biosensors and Bioelectronics
    6. Erica Barini, Gudrun Plotzky, Yulia Mordashova, Jonas Hoppe, Esther Rodriguez-Correa, Sonja Julier, Florie LePrieult, Ina Mairhofer, Mario Mezler, Sandra Biesinger, Miroslav Cik, Marcus W Meinhardt, Ebru Ercan-Herbst, Dagmar Ehrnhoefer, Andreas Striebinger, Karen Bodie, Corinna Klein, Laura Gasparini, Kerstin Schlegel:
      Tau in the brain interstitial fluid is fragmented and seeding-competent
      BioRXiv

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  • DNA Damage in Cancer (DDC)
    1. Serçin Ö, Reither S, Roidos P, Ballin N, Palikyras S, Baginska A, Rein K, Llamazares M, Halavatyi A, Winter H, Muley T, Jurkowska RZ, Abdollahi A, Zenke FT, Neumann B, Mardin BR (2019):
      A solid-phase transfection platform for arrayed CRISPR screens
      Molecular Systems Biology 15 (12)
    2. Drainas AP, Lambuta RA, Ivanova I, Serçin Ö, Sarropoulos I, Smith ML, Efthymiopoulos T, Raeder B, Stütz AM, Waszak SM, Mardin BR, Korbel JO (2020):
      Genome-wide Screens Implicate Loss of Cullin Ring Ligase 3 in Persistent Proliferation and Genome Instability in TP53-Deficient Cells
      Cell Reports 31(1)
    3. Roidos P, Sungalee S, Benfatto S, Serçin Ö, Stütz AM, Abdollahi A, Mauer J, Zenke FT, Korbel JO, Mardin BR (2020):
      A scalable CRISPR/CAS)-based fluorescent reporter assay to study DNA double-strand break repair choice
      Nature Communications 11, 4077 (2020)

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