Team IAA

Completed Projects · Platform Technologies

Team IAA

Rapid Identification of Auto-Antigens in Autoimmune Diseases

The team is seeking new platform technologies or concepts which lead to identification of antigens recognized by T-cells involved in autoimmune responses. The objective of the group is to deconvolute the autoimmune T-cell receptor (TCR) repertoire functionally with respect to unknown cognate peptide: HLA complexes. We will use high-throughput screening approaches coupling sequence to specificity in order to identify critical points of attack in the treatment of autoimmune diseases.

The research of this team was kindly sponsored by Janssen.

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