45 search results for “Oncology”
Appearances
Our management and project teams are regularly represented at events and report there about BioMed X and our ongoing research.
Scientific Publications
For us at BioMed X, publishing the results of our research projects in peer-reviewed journals is key. We also share results at national and international meetings and workshops. We think this is vital to building collaborations and stimulating cross-fertilization of ideas and methods.
SIG Tools and Methods
At the BioMed X Institute, we are working with different state-of-the-art research tools and methods, emerging from the different research projects. As a Special Interest Group, we continuously grow our internal spectrum of laboratory tools and methods.
Team IMT
Completed Projects · Oncology Team IMT Immunosuppressive Microenvironment of Tumors Solid tumors are complex microenvironments composed of cancer and immune cells that interact through various regulatory networks. Although CD8 T-cells may recognize and kill tumor cells, their function is impaired by cells such as regulatory T-cells, tumor-associated macrophages (TAM), and myeloid-derived suppresso…
Team SKI
Completed Projects · Oncology Team SKI Selective Kinase Inhibitors Protein kinases have been a major target of drug discovery programs for many years due to their central roles in signaling pathways involved in the formation and progression of human cancer, inflammation and Alzheimer’s disease. Most kinase inhibitors that are currently approved and in development bind to the highly conserved ATP-b…
Team MSC
Completed Projects · Oncology Team MSC Metabolism and Signaling in Cancer Owing to stressful microenvironments and the accumulation of mutations favoring adaption, cancer cells frequently show alterations in metabolic and other signaling circuits compared with normal cells. As a consequence, cancer cells show increased dependence on certain proteins or stress-support pathways, which themselves mig…
Completed Projects
Since 2013 we have started 20 research groups and successfully completed 12 projects. After a project term of 5 years, all data, materials, and intellectual property rights are transferred to the sponsoring partners.
Our Industry Partners
Accelerate the pace of innovation in biomedical research. Become a partner and join the BioMed X Institute.
Our Team
We are a team of highly diverse people from many different countries working on the same ambitious goals.
About BioMed X
BioMed X is an independent research institute operating at the interface between academia and industry.
Team RSC
Splicing of mRNA is a crucial process in eukaryotic gene expression regulation, and aberrant splicing plays a critical role in the pathogenesis of several molecular subtypes of cancer. Such splicing abnormalities can lead to constitutive activity of oncogenes, reduced expression of tumor suppressors, or drug resistance. Our team is seeking to identify key molecular mechanisms that generate mRNA sp…
Contact
Contact us If you have questions about the BioMed X Institute, please do not hesitate to contact us. BioMed X GmbH Im Neuenheimer Feld 515 69120 Heidelberg, Germany +49 6221 426 11 0 +49 6221 426 11 22 info@bio.mx Im Neuenheimer Feld 515 Management & Support Team Team IEB Group Leader: Martin Resnik Docampo Team EPD Group Leader: Ebru Ercan Herbst Team TMI Group Leader: Kyungbo Kim Team PTA Group…
Team DDC
Often termed as a disease of the genome, cancer is the result of random acquisition of mutations that activate oncogenes and inactivate tumor suppressors. Consequently, cellular processes including cell cycle control, transcription, apoptosis and DNA repair are affected, conferring incremental growth advantages to cells and fomenting tumorigenesis.
Research Teams
We identify and attract the best early-career researchers at the best universities and research institutions who are interested to work on our challenges to make a real impact in research for the benefit of patients.
Our Events
Interested to learn more about our innovation model and our research projects? Check out our list of events.